phage display systems

by cataliesw on Dec 27th, 2024 06:31 AM

Serving as a powerful tool for high-throughput screening of molecular interactions, phage display has been proven the most popular among all available display techniques. By the genetic manipulation of genes of surface proteins on filamentous phages, target of interest will be expressed on the surface of phage to support the biopanning. Instead of intact phage, current phage display systems employ various bacteriophage vectors, including filamentous M13, T7, bacteriophage lambda (λ phage) and T4 phage display systems.